For the smartie pants who’s not verified and doesn’t appear to have google…… here you are Canning 101:
Popper is a
slang term given broadly to ******* of the
chemical class called
alkyl nitrites that are
inhaled. Most widely sold products include the original
isoamyl nitrite or isopentyl nitrite, and
isopropyl nitrite.
Isobutyl nitrite is also widely used but is banned in the
European Union. In some countries, poppers are labeled or packaged as room deodorizers, leather polish, nail polish remover, or videotape head cleaner to evade anti-******* laws.
Popper use has a relaxation effect on
involuntary smooth muscles, such as those in the throat and anus.
[1][2] It is used for practical purposes to facilitate
anal sex by increasing ******* flow and relaxing
sphincter muscles.
[3]The ******* is also used for
recreational *******purposes, typically for the "high" or "rush" that the ******* can create.
Poppers were part of club culture from the mid-1970s
disco scene and returned to popularity in the 1980s and 1990s
ravescene.
19th-century discovery
The French chemist
Antoine Jérôme Balardsynthesized
amyl nitrite in 1844.
[6] Sir Thomas Lauder Brunton, a Scottish physician born in the year of amyl nitrite's first synthesis, documented its clinical use to treat
angina pectoris in 1867 when patients experiencing chest pains would experience complete relief after inhalation.
[7] Brunton was inspired by earlier work with the same agent, performed by
Arthur Gamgee and
Benjamin Ward Richardson.
[7] Brunton reasoned that the angina sufferer's pain and discomfort could be reduced by administering amyl nitrite—to dilate the coronary arteries of patients, thus improving ******* flow to the heart muscle.
[7]
Amyl nitrites were originally enclosed in a glass mesh called "pearls". The usual administration of these pearls was done by crushing them between the fingers, followed by a popping sound. This administration process seems to be the origin of the
slang term "poppers". It was then administered by direct inhalation of the vapours or inhalation through silk that covered the capsule. Brunton found that amyl nitrites had effects of dilating ******* vessels and flushing of the face. Butyl nitrites were also documented around the late 1890s by Brunton and despite being found to have generally the same effects as amyl nitrites, they were never used as a clinical alternative to amyl nitrates. Brunton also found that propyl nitrites had the same effects as well.
[8][9]
20th-century presence in 1960s disco and 1970s gay cultur
Although amyl nitrite is known for its practical therapeutic applications, the first documented case of recreational use was in 1964.
[10][11] The poppers "craze" began in the early 1970s in the
Gay male community in gay bars, discothèques and
bathhouses,
[12] marking its prominent presence in gay culture.
[13] It was packaged and sold pharmaceutically in fragile glass ampoules wrapped in cloth sleeves which, when crushed or "popped" in the fingers, released the amyl nitrite for inhalation, hence the colloquialism poppers.
[12] The term extended to the ******* in any form as well as to other ******* with similar effects, e.g.
butyl nitrite which is packaged under a variety of trade names in small bottles.
[12]
In the late 1970s
Time magazine
[14] and
The Wall Street Journal[15] reported that popper use among
gay men began as a way to enhance sexual pleasure, but "quickly spread to avant-garde heterosexuals". A series of interviews conducted in the late 1970s revealed a wide spectrum of users.
[14]
Poppers come in liquid form, but this liquid is not directly consumed. When the bottle is opened, the vapors are inhaled, rather than the liquid. This is typically done through the nasal cavities, commonly directly from the bottle (avoiding touching the bottle to the skin) or with the help of small inhalators.
Inhaling nitrites relaxes
smooth musclesthroughout the body, as well as
sphinctermuscles of the
anus and the
vagina.
[17] Smooth muscle surrounds the body's ******* vessels and when relaxed causes these vessels to dilate resulting in an immediate increase in
heart rate and ******* flow throughout the body, producing a sensation of heat and excitement that usually lasts for a couple of minutes.
[18][19]When these vessels dilate, a further result is an immediate decrease in
******* pressure.
[20]
. 
